PTGS2 -> CellMigration
CCL20 -> CellMigration
IL8 -> CellMigration
CTGF -> CellMigration
DAG -> PKC
AKAP12 -| PKC
Ca -> PKC
Erk -> RSK
HBEGF -> EGFR
EGF -> EGFR
PLC_g -> DAG
Erk -> cMYC
Erk -> EGR1
PAK2 -> JNK
Mkk4 -> JNK
Mekk7 -> JNK
Cdc42_Rac1 -> MLK3
CyclinD -> Proliferation
CDK2 -> Proliferation
SOS -> Ras
ECM -> Integrins
Mek -> Erk
DOCK180 -> Cdc42_Rac1
Akt -> Cdc42_Rac1
Ras -> Cdc42_Rac1
p38 -> cJUN
JNK -> cJUN
CyclinD -> CDK2
CDKN1A -| CDK2
CDKN2A -| CDK2
uPA -> Plasmin
PAI_1 -> Plasmin
Erk -> IL8
p38 -> IL8
EGFR -> Shc
Fak -> Shc
MET -> Shc
EGFR -> PLC_g
MET -> PLC_g
Erk -> CTGF
p38 -> CTGF
Cdc42_Rac1 -> Mekk4
Cdc42_Rac1 -> PAK2
STAT3 -> CDKN1A
Elk1 -> CDKN2A
ETS -> CDKN2A
CRKL -> C3G
Grb2 -> CRKL
Erk -> STAT3
Mekk1 -> Mekk7
Cdc42_Rac1 -> PAK1
MLK3 -> Mkk6
PKC -> Raf
Ras -> Raf
PAK3 -> Raf
Plasmin -> MMP1_10
CRKL -> DOCK180
Elk1 -> CyclinD
ATF2 -> CyclinD
C3G -> Rap1
Cdc42_Rac1 -> PAK3
Erk -> ETS
uPAR -> uPA
RSK -> CREB
EGFR -> PI3K
Fak -> PI3K
MET -> PI3K
Grb2 -> SOS
Mekk4 -> Mkk4
Mekk1 -> Mkk4
MLK3 -> Mkk4
Erk -> cFOS
Rap1 -> Fak
PTEN -| Fak
Integrins -> Fak
Shc -> Grb2
MLK3 -> Mkk3
AP1 -> uPAR
Raf -> Mek
Mekk1 -> Mek
Erk -> CCL20
p38 -> ATF2
JNK -> ATF2
cJUN -> PTGS2
cFOS -> PTGS2
ATF2 -> PTGS2
MMP1_10 -> ECM
PAK1 -> p38
DUSP1 -| p38
Mkk3 -> p38
Mkk6 -> p38
Cdc42_Rac1 -> Mekk1
PLC_g -> IP3
IP3 -> Ca
Erk -> Elk1
JNK -> Elk1
HGF -> MET
cJUN -> AP1
cFOS -> AP1
Erk -> HBEGF
p38 -> HBEGF
PI3K -> Akt
PTEN -| Akt
$AP1: (cFOS & cJUN)
$ATF2: (JNK & p38)
$Akt: (PI3K & !PTEN)
$C3G: CRKL
$CCL20: Erk
$CDK2: (CyclinD & (!CDKN2A | !CDKN1A))
$CDKN1A: STAT3
$CDKN2A: (Elk1 | ETS)
$CREB: RSK
$CRKL: Grb2
$CTGF: (Erk | p38)
$Ca: IP3
$Cdc42_Rac1: (Akt & (DOCK180 & Ras))
$CellMigration: (IL8 & ((PTGS2 & CCL20) & CTGF))
$CyclinD: (Elk1 | ATF2)
$DAG: PLC_g
$DOCK180: CRKL
$ECM: MMP1_10
$EGFR: (HBEGF | EGF)
$EGR1: Erk
$ETS: Erk
$Elk1: (JNK | Erk)
$Erk: Mek
$Fak: ((Integrins & Rap1) & !PTEN)
$Grb2: Shc
$HBEGF: (Erk | p38)
$IL8: (Erk | p38)
$IP3: PLC_g
$Integrins: ECM
$JNK: ((Mekk7 & Mkk4) | PAK2)
$MET: HGF
$MLK3: Cdc42_Rac1
$MMP1_10: Plasmin
$Mek: (Mekk1 | Raf)
$Mekk1: Cdc42_Rac1
$Mekk4: Cdc42_Rac1
$Mekk7: Mekk1
$Mkk3: MLK3
$Mkk4: ((Mekk4 | Mekk1) | MLK3)
$Mkk6: MLK3
$PAK1: Cdc42_Rac1
$PAK2: Cdc42_Rac1
$PAK3: Cdc42_Rac1
$PI3K: ((EGFR & Fak) | MET)
$PKC: ((DAG & Ca) & !AKAP12)
$PLC_g: (EGFR | MET)
$PTGS2: ((cFOS & cJUN) | ATF2)
$Plasmin: (uPA & PAI_1)
$Proliferation: (CDK2 & CyclinD)
$RSK: Erk
$Raf: (Ras & (PKC & PAK3))
$Rap1: C3G
$Ras: SOS
$SOS: Grb2
$STAT3: Erk
$Shc: ((MET | Fak) | EGFR)
$cFOS: Erk
$cJUN: (JNK & p38)
$cMYC: Erk
$p38: (PAK1 | ((Mkk3 & Mkk6) & !DUSP1))
$uPA: uPAR
$uPAR: AP1